It takes three to the DNA damage response tango

The DNA damage response is robustly activated by DNA double-strand breaks and controlled by three apical protein kinases of the PI3-kinase-related protein kinase (PIKK) family: ataxia-telangiectasia, mutated (ATM), ataxia-telangiectasia and Rad3-related (ATR) and DNA-dependent protein kinase (DNA-PK...

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Bibliographic Details
Main Authors: Sapir Schlam-Babayov, Yael Ziv, Yosef Shiloh
Format: Article
Language:English
Published: Taylor & Francis Group 2021-03-01
Series:Molecular & Cellular Oncology
Subjects:
Online Access:http://dx.doi.org/10.1080/23723556.2021.1881395