A DNA vaccine delivered by dermal electroporation fully protects cynomolgus macaques against Lassa fever

A DNA vaccine delivered by dermal electroporation fully protects cynomolgus macaques against Lassa fever

Lassa virus (LASV) is an ambisense RNA virus in the Arenaviridae family and is the etiological agent of Lassa fever, a severe hemorrhagic disease endemic to West and Central Africa. There are no US Food and Drug Administration (FDA)-licensed vaccines available to prevent Lassa fever. in our previous...

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Bibliographic Details
Main Authors: Kathleen A. Cashman, Eric R. Wilkinson, Carl I. Shaia, Paul R. Facemire, Todd M. Bell, Jeremy J. Bearss, Joshua D. Shamblin, Suzanne E. Wollen, Kate E. Broderick, Niranjan Y. Sardesai, Connie S. Schmaljohn
Format: Article
Language:English
Published: Taylor & Francis Group 2017-12-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
lassa fever
dna vaccine
electroporation
Online Access:http://dx.doi.org/10.1080/21645515.2017.1356500

Internet

http://dx.doi.org/10.1080/21645515.2017.1356500

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