Combinatorial Treatment of Birinapant and Zosuquidar Enhances Effective Control of HBV Replication In Vivo

Combinatorial Treatment of Birinapant and Zosuquidar Enhances Effective Control of HBV Replication In Vivo

Chronic hepatitis B virus (HBV) infection remains a global health threat and affects hundreds of millions worldwide. Small molecule compounds that mimic natural antagonists of inhibitor of apoptosis (IAP) proteins, known as Smac-mimetics (second mitochondria-derived activator of caspases-mimetics),...

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Bibliographic Details
Main Authors: Emma Morrish, Liana Mackiewicz, Natasha Silke, Marc Pellegrini, John Silke, Gabriela Brumatti, Gregor Ebert
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Viruses
Subjects:
HBV
inhibitor of apoptosis proteins
IAP
IAP antagonist
Smac-mimetics
TNF
Online Access:https://www.mdpi.com/1999-4915/12/8/901

Internet

https://www.mdpi.com/1999-4915/12/8/901

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