A fluorescent plasmonic biochip assay for multiplex screening of diagnostic serum antibody targets in human Lyme disease.

Lyme disease (LD) diagnosis using the current two-tier algorithm is constrained by low sensitivity for early-stage infection and ambiguity in determining treatment response. We recently developed a protein microarray biochip that measures diagnostic serum antibody targets using grating-coupled fluor...

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Bibliographic Details
Main Authors: Eunice Chou, Erica Lasek-Nesselquist, Benjamin Taubner, Arturo Pilar, Ernest Guignon, William Page, Yi-Pin Lin, Nathaniel C Cady
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0228772