Individual MHCI restricted T-cell receptors are characterized by a unique peptide recognition signature
Effective immunity requires that a limited TCR repertoire is able to recognize a vast number of foreign peptide-MHCI. This challenge is overcome by the ability of individual TCRs to recognize large numbers of peptides. Recently, it was demonstrated that MHCI-restricted TCRs can recognize up to 10^6...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2013-07-01
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| Series: | Frontiers in Immunology |
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| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00199/full |