Alternative splicing of apoptosis genes promotes human T cell survival

Alternative splicing occurs in the vast majority of human genes, giving rise to distinct mRNA and protein isoforms. We, and others, have previously identified hundreds of genes that change their isoform expression upon T cell activation via alternative splicing; however, how these changes link activ...

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Bibliographic Details
Main Authors: Davia Blake, Caleb M Radens, Max B Ferretti, Matthew R Gazzara, Kristen W Lynch
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-10-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/80953