Stromal heterogeneity may explain increased incidence of metaplastic breast cancer in women of African descent

Abstract The biologic basis of genetic ancestry-dependent variability in disease incidence and outcome is just beginning to be explored. We recently reported enrichment of a population of ZEB1-expressing cells located adjacent to ductal epithelial cells in normal breasts of women of African ancestry...

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Bibliographic Details
Main Authors: Brijesh Kumar, Aditi S. Khatpe, Jiang Guanglong, Katie Batic, Poornima Bhat-Nakshatri, Maggie M. Granatir, Rebekah Joann Addison, Megan Szymanski, Lee Ann Baldridge, Constance J. Temm, George Sandusky, Sandra K. Althouse, Michele L. Cote, Kathy D. Miller, Anna Maria Storniolo, Harikrishna Nakshatri
Format: Article
Language:English
Published: Nature Portfolio 2023-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-41473-6