Metabolic Engineering and Adaptive Evolution for Efficient Production of l-Lactic Acid in Saccharomyces cerevisiae

Metabolic Engineering and Adaptive Evolution for Efficient Production of l-Lactic Acid in Saccharomyces cerevisiae

ABSTRACT l-Lactic acid (LA) is a three-carbon hydroxycarboxylic acid with extensive applications in food, cosmetic, agricultural, pharmaceutical, and bioplastic industries. However, microbial LA production is limited by its intrinsic inefficiency of cellular metabolism. Here, pathway engineering was...

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Bibliographic Details
Main Authors: Pan Zhu, Rui Luo, Yize Li, Xiulai Chen
Format: Article
Language:English
Published: American Society for Microbiology 2022-12-01
Series:Microbiology Spectrum
Subjects:
metabolic engineering
adaptive evolution
l-lactic acid
Saccharomyces cerevisiae
Online Access:https://journals.asm.org/doi/10.1128/spectrum.02277-22

Internet

https://journals.asm.org/doi/10.1128/spectrum.02277-22

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