Multimodal classification of molecular subtypes in pediatric acute lymphoblastic leukemia

Multimodal classification of molecular subtypes in pediatric acute lymphoblastic leukemia

Abstract Genomic analyses have redefined the molecular subgrouping of pediatric acute lymphoblastic leukemia (ALL). Molecular subgroups guide risk-stratification and targeted therapies, but outcomes of recently identified subtypes are often unclear, owing to limited cases with comprehensive profilin...

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Main Authors: Olga Krali, Yanara Marincevic-Zuniga, Gustav Arvidsson, Anna Pia Enblad, Anders Lundmark, Shumaila Sayyab, Vasilios Zachariadis, Merja Heinäniemi, Janne Suhonen, Laura Oksa, Kaisa Vepsäläinen, Ingegerd Öfverholm, Gisela Barbany, Ann Nordgren, Henrik Lilljebjörn, Thoas Fioretos, Hans O. Madsen, Hanne Vibeke Marquart, Trond Flaegstad, Erik Forestier, Ólafur G. Jónsson, Jukka Kanerva, Olli Lohi, Ulrika Norén-Nyström, Kjeld Schmiegelow, Arja Harila, Mats Heyman, Gudmar Lönnerholm, Ann-Christine Syvänen, Jessica Nordlund
Format: Article
Language:English
Published: Nature Portfolio 2023-12-01
Series:npj Precision Oncology
Online Access:https://doi.org/10.1038/s41698-023-00479-5

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https://doi.org/10.1038/s41698-023-00479-5

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