Novel Insights into the Sinoatrial Node in Single-Cell RNA Sequencing: From Developmental Biology to Physiological Function

Novel Insights into the Sinoatrial Node in Single-Cell RNA Sequencing: From Developmental Biology to Physiological Function

Normal cardiac automaticity is dependent on the pacemaker cells of the sinoatrial node (SAN). Insufficient cardiac pacemaking leads to the development of sick sinus syndrome (SSS). Since currently available pharmaceutical drugs and implantable pacemakers are only partially effective in managing SSS,...

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Bibliographic Details
Main Authors: Wei Fan, Chao Yang, Xiaojie Hou, Juyi Wan, Bin Liao
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Journal of Cardiovascular Development and Disease
Subjects:
sinoatrial node
single-cell RNA sequencing
transcription factors
signaling pathways
molecular regulation
Online Access:https://www.mdpi.com/2308-3425/9/11/402

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https://www.mdpi.com/2308-3425/9/11/402

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