Tbx6 controls left-right asymmetry through regulation of Gdf1
The Tbx6 transcription factor plays multiple roles during gastrulation, somite formation and body axis determination. One of the notable features of the Tbx6 homozygous mutant phenotype is randomization of left/right axis determination. Cilia of the node are morphologically abnormal, leading to the...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2018-05-01
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Series: | Biology Open |
Subjects: | |
Online Access: | http://bio.biologists.org/content/7/5/bio032565 |