Treatment of Marmoset Intracerebral Hemorrhage with Humanized Anti-HMGB1 mAb

Treatment of Marmoset Intracerebral Hemorrhage with Humanized Anti-HMGB1 mAb

Intracerebral hemorrhage (ICH) is recognized as a severe clinical problem lacking effective treatment. High mobility group box-1 (HMGB1) exhibits inflammatory cytokine-like activity once released into the extracellular space from the nuclei. We previously demonstrated that intravenous injection of r...

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Bibliographic Details
Main Authors: Dengli Wang, Daiki Ousaka, Handong Qiao, Ziyi Wang, Kun Zhao, Shangze Gao, Keyue Liu, Kiyoshi Teshigawara, Kenzo Takada, Masahiro Nishibori
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Cells
Subjects:
intracerebral hemorrhage
HMGB1
antibody therapy
non-human primate
Online Access:https://www.mdpi.com/2073-4409/11/19/2970

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https://www.mdpi.com/2073-4409/11/19/2970

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