Phagocytosis of platelets opsonized with differently glycosylated anti-HLA hIgG1 by monocyte-derived macrophages

Phagocytosis of platelets opsonized with differently glycosylated anti-HLA hIgG1 by monocyte-derived macrophages

Immune-mediated platelet refractoriness (PR) remains a significant problem in the setting of platelet transfusion and is predominantly caused by the presence of alloantibodies directed against class I human leukocyte antigens (HLA). Opsonization of donor platelets with these alloantibodies can resul...

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Bibliographic Details
Main Authors: Thijs L. J. van Osch, Juulke Steuten, Jan Nouta, Carolien A. M. Koeleman, Arthur E. H. Bentlage, Sebastiaan Heidt, Arend Mulder, Jan Voorberg, S. Marieke van Ham, Manfred Wuhrer, Anja ten Brinke, Gestur Vidarsson
Format: Article
Language:English
Published: Taylor & Francis Group 2023-01-01
Series:Platelets
Subjects:
alloimmunization
anti-hla
fc glycosylation
phagocytosis
platelet transfusion
Online Access:http://dx.doi.org/10.1080/09537104.2022.2129604

Internet

http://dx.doi.org/10.1080/09537104.2022.2129604

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