Serum glial cell line-derived neurotrophic factor (GDNF) a potential biomarker of executive function in Parkinson’s disease

ObjectiveEvidence shows that the impairment of executive function (EF) is mainly attributed to the degeneration of frontal-striatal dopamine pathway. Glial cell line-derived neurotrophic factor (GDNF), as the strongest protective neurotrophic factor for dopaminergic neurons (DANs), may play a role i...

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Bibliographic Details
Main Authors: Shu-Yan Tong, Rui-Wen Wang, Qian Li, Yi Liu, Xiao-Yan Yao, De-Qin Geng, Dian-Shuai Gao, Chao Ren
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2023.1136499/full