Ca2+ Regulates Dimerization of the BAR Domain Protein PICK1 and Consequent Membrane Curvature

Ca2+ Regulates Dimerization of the BAR Domain Protein PICK1 and Consequent Membrane Curvature

Bin-Amphiphysin-Rvs (BAR) domain proteins are critical regulators of membrane geometry. They induce and stabilize membrane curvature for processes, such as clathrin-coated pit formation and endosomal membrane tubulation. BAR domains form their characteristic crescent-shaped structure in the dimeric...

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Bibliographic Details
Main Authors: Georgiana F. Stan, Deborah K. Shoemark, Dominic Alibhai, Jonathan G. Hanley
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Molecular Neuroscience
Subjects:
BAR domain
endocytosis
PDZ domain
calcium
synaptic plasticity
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2022.893739/full

Internet

https://www.frontiersin.org/articles/10.3389/fnmol.2022.893739/full

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