Comprehensive systems biology analysis of microRNA-101-3p regulatory network identifies crucial genes and pathways in hepatocellular carcinoma

Comprehensive systems biology analysis of microRNA-101-3p regulatory network identifies crucial genes and pathways in hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is a leading cause of cancer-related mortality worldwide. This study aimed to explore the role of hsa-miR-101-3p in HCC pathogenesis by identifying key genes and pathways. A comprehensive bioinformatics analysis revealed twelve hub genes (ETNK1, BICRA, IL1R1, KDM3A, AR...

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Bibliographic Details
Main Authors: Nasim Rahimi-Farsi, Abozar Ghorbani, Negar Mottaghi-Dastjerdi, Taha Shahbazi, Fatemeh Bostanian, Parvin Mohseni, Fateme Yazdani
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Journal of Genetic Engineering and Biotechnology
Subjects:
Gene network
hsa-miR-101-3p
Hepatocellular carcinoma
Protein-protein interaction
Online Access:http://www.sciencedirect.com/science/article/pii/S1687157X25000150

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http://www.sciencedirect.com/science/article/pii/S1687157X25000150

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