A Representative GIIA Phospholipase A<sub>2</sub> Activates Preadipocytes to Produce Inflammatory Mediators Implicated in Obesity Development

A Representative GIIA Phospholipase A<sub>2</sub> Activates Preadipocytes to Produce Inflammatory Mediators Implicated in Obesity Development

Adipose tissue secretes proinflammatory mediators which promote systemic and adipose tissue inflammation seen in obesity. Group IIA (GIIA)-secreted phospholipase A<sub>2</sub> (sPLA<sub>2</sub>) enzymes are found to be elevated in plasma and adipose tissue from obese patients...

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Bibliographic Details
Main Authors: Elbio Leiguez, Priscila Motta, Rodrigo Maia Marques, Bruno Lomonte, Suely Vilela Sampaio, Catarina Teixeira
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Biomolecules
Subjects:
phospholipase A<sub>2</sub>
preadipocytes
prostaglandins
adipokines
cytokines
EP receptors
Online Access:https://www.mdpi.com/2218-273X/10/12/1593

Internet

https://www.mdpi.com/2218-273X/10/12/1593

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