End-to-end pipeline for differential analysis of pausing in ribosome profiling data

Summary: Ribosome profiling is a powerful technique which maps the distribution of ribosomes along mRNAs to analyze translation genome-wide. Ribosome density can be affected by multiple factors, such as changes to translation initiation or elongation rates. We describe the application of a metric fo...

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Bibliographic Details
Main Authors: Keegan Flanagan, Wanxin Li, Ethan J. Greenblatt, Khanh Dao Duc
Format: Article
Language:English
Published: Elsevier 2022-09-01
Series:STAR Protocols
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666166722004853