Nanodosimetric Calculations of Radiation-Induced DNA Damage in a New Nucleus Geometrical Model Based on the Isochore Theory

Nanodosimetric Calculations of Radiation-Induced DNA Damage in a New Nucleus Geometrical Model Based on the Isochore Theory

Double-strand breaks (DSBs) in nuclear DNA represents radiation-induced damage that has been identified as particularly deleterious. Calculating this damage using Monte Carlo track structure modeling could be a suitable indicator to better assess and anticipate the side-effects of radiation therapy....

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Bibliographic Details
Main Authors: Yann Thibaut, Nicolas Tang, Hoang Ngoc Tran, Aurélie Vaurijoux, Carmen Villagrasa, Sébastien Incerti, Yann Perrot
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:International Journal of Molecular Sciences
Subjects:
DNA damage simulation
Geant4-DNA
isochores
Online Access:https://www.mdpi.com/1422-0067/23/7/3770

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https://www.mdpi.com/1422-0067/23/7/3770

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