Magnesium and Morphine in the Treatment of Chronic Neuropathic Pain–A Biomedical Mechanism of Action

The effectiveness of opioids in the treatment of neuropathic pain is limited. It was demonstrated that magnesium ions (Mg<sup>2+</sup>), physiological antagonists of N-methyl-D-aspartate receptor (NMDAR), increase opioid analgesia in chronic pain. Our study aimed to determine the molecul...

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Bibliographic Details
Main Authors: Kamila Kulik, Barbara Żyżyńska-Granica, Agnieszka Kowalczyk, Przemysław Kurowski, Małgorzata Gajewska, Magdalena Bujalska-Zadrożny
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/22/24/13599