Empirical Bayes functional models for hydrogen deuterium exchange mass spectrometry

A statistical analysis approach for HDX-MS time series data incorporates correlations in time, reducing false positives and improving statistical power and data interpretation.

Bibliographic Details
Main Authors: Oliver M. Crook, Chun-wa Chung, Charlotte M. Deane
Format: Article
Language:English
Published: Nature Portfolio 2022-06-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-022-03517-3