Association between the <i>TPMT*3C</i> (rs1142345) Polymorphism and the Risk of Death in the Treatment of Acute Lymphoblastic Leukemia in Children from the Brazilian Amazon Region

Association between the <i>TPMT*3C</i> (rs1142345) Polymorphism and the Risk of Death in the Treatment of Acute Lymphoblastic Leukemia in Children from the Brazilian Amazon Region

Acute lymphoblastic leukemia (ALL) is the leading cause of death from pediatric cancer worldwide. However, marked ethnic disparities are found in the treatment of childhood ALL with less effective results and higher mortality rates being obtained in populations with a high level of Native American a...

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Bibliographic Details
Main Authors: Darlen Cardoso de Carvalho, Luciana Pereira Colares Leitão, Fernando Augusto Rodrigues Mello Junior, Alayde Vieira Wanderley, Tatiane Piedade de Souza, Roberta Borges Andrade de Sá, Amanda Cohen-Paes, Marianne Rodrigues Fernandes, Sidney Santos, André Salim Khayat, Paulo Pimentel de Assumpção, Ney Pereira Carneiro dos Santos
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Genes
Subjects:
acute lymphoblastic leukemia
pediatrics
TPMT
polymorphism
pharmacogenetics
mortality
Online Access:https://www.mdpi.com/2073-4425/11/10/1132

Internet

https://www.mdpi.com/2073-4425/11/10/1132

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