SNHG15 is a bifunctional MYC-regulated noncoding locus encoding a lncRNA that promotes cell proliferation, invasion and drug resistance in colorectal cancer by interacting with AIF

SNHG15 is a bifunctional MYC-regulated noncoding locus encoding a lncRNA that promotes cell proliferation, invasion and drug resistance in colorectal cancer by interacting with AIF

Abstract Background Thousands of long noncoding RNAs (lncRNAs) are aberrantly expressed in various types of cancers, however our understanding of their role in the disease is still very limited. Methods We applied RNAseq analysis from patient-derived data with validation in independent cohort of pat...

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Bibliographic Details
Main Authors: Morvarid Saeinasab, Ahmad Reza Bahrami, Jovanna González, Francesco P. Marchese, Dannys Martinez, Seyed Javad Mowla, Maryam M. Matin, Maite Huarte
Format: Article
Language:English
Published: BMC 2019-04-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
SNHG15
Colorectal cancer
lncRNA
Survival
Drug resistance
AIF
Online Access:http://link.springer.com/article/10.1186/s13046-019-1169-0

Internet

http://link.springer.com/article/10.1186/s13046-019-1169-0

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