Synthesis of Bio-Inspired 1,3-Diarylpropene Derivatives via Heck Cross-Coupling and Cytotoxic Evaluation on Breast Cancer Cells

Synthesis of Bio-Inspired 1,3-Diarylpropene Derivatives via Heck Cross-Coupling and Cytotoxic Evaluation on Breast Cancer Cells

The Heck cross-coupling reaction is a well-established chemical tool for the synthesis of unsaturated compounds by formation of a new C-C bond. In this study, 1,3-diarylpropene derivatives, designed as structural analogues of stilbenoids and dihydrostilbenoids, were synthesised by the palladium-cata...

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Bibliographic Details
Main Authors: Aik Sian Tan, Jaymeer Singh, Nurul Syafiqah Rezali, Musthahimah Muhamad, Nik Nur Syazni Nik Mohamed Kamal, Yvan Six, Mohamad Nurul Azmi
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Molecules
Subjects:
Heck cross-coupling
1,3-diarylpropene
β-hydride elimination
cytotoxic effects
breast cancer cells
Online Access:https://www.mdpi.com/1420-3049/27/17/5373

Internet

https://www.mdpi.com/1420-3049/27/17/5373

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