hGC33-Modified and Sorafenib-Loaded Nanoparticles have a Synergistic Anti-Hepatoma Effect by Inhibiting Wnt Signaling Pathway

hGC33-Modified and Sorafenib-Loaded Nanoparticles have a Synergistic Anti-Hepatoma Effect by Inhibiting Wnt Signaling Pathway

Abstract Delivery of tumor-specific inhibitors is a challenge in cancer treatment. Antibody-modified nanoparticles can deliver their loaded drugs to tumor cells that overexpress specific tumor-associated antigens. Here, we constructed sorafenib-loaded polyethylene glycol-b-PLGA polymer nanoparticles...

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Bibliographic Details
Main Authors: Jing Shen, Wenpeng Cai, Yongfang Ma, Ruyue Xu, Zhen Huo, Li Song, Xinyin Qiu, Yinci Zhang, Amin Li, Weiya Cao, Shuping Zhou, Xiaolong Tang
Format: Article
Language:English
Published: SpringerOpen 2020-11-01
Series:Nanoscale Research Letters
Subjects:
Glypican-3
Hepatocellular carcinoma
Targeted therapy
Wnt signal
Online Access:http://link.springer.com/article/10.1186/s11671-020-03451-5

Internet

http://link.springer.com/article/10.1186/s11671-020-03451-5

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