Drug Discovery Platform Targeting M. tuberculosis with Human Embryonic Stem Cell-Derived Macrophages

Drug Discovery Platform Targeting M. tuberculosis with Human Embryonic Stem Cell-Derived Macrophages

Summary: A major limitation in anti-tuberculosis drug screening is the lack of reliable and scalable models for homogeneous human primary macrophage cells of non-cancer origin. Here we report a modified protocol for generating homogeneous populations of macrophage-like cells from human embryonic ste...

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Bibliographic Details
Main Authors: Hyo-Won Han, Hyang-Hee Seo, Hye-Yeong Jo, Hyeong-jun Han, Virgínia C.A. Falcão, Vincent Delorme, Jinyeong Heo, David Shum, Jang-Hoon Choi, Jin-Moo Lee, Seung Hun Lee, Hye-Ryeon Heo, Seok-Ho Hong, Mi-Hyun Park, Rajesh K. Thimmulappa, Jung-Hyun Kim
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671119303637

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http://www.sciencedirect.com/science/article/pii/S2213671119303637

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