Macrophage Polarization States in the Tumor Microenvironment

Macrophage Polarization States in the Tumor Microenvironment

The M1/M2 macrophage paradigm plays a key role in tumor progression. M1 macrophages are historically regarded as anti-tumor, while M2-polarized macrophages, commonly deemed tumor-associated macrophages (TAMs), are contributors to many pro-tumorigenic outcomes in cancer through angiogenic and lymphan...

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Bibliographic Details
Main Authors: Ava J. Boutilier, Sherine F. Elsawa
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:International Journal of Molecular Sciences
Subjects:
tumor-associated macrophage
tumor microenvironment
metastasis
cytokine signaling
polarization
malignancy
Online Access:https://www.mdpi.com/1422-0067/22/13/6995

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https://www.mdpi.com/1422-0067/22/13/6995

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