Functional Characterization of a Spectrum of Novel Romano-Ward Syndrome <i>KCNQ1</i> Variants

Functional Characterization of a Spectrum of Novel Romano-Ward Syndrome <i>KCNQ1</i> Variants

The <i>KCNQ1</i> gene encodes the α-subunit of the cardiac voltage-gated potassium (Kv) channel KCNQ1, also denoted as Kv7.1 or KvLQT1. The channel assembles with the ß-subunit KCNE1, also known as minK, to generate the slowly activating cardiac delayed rectifier current <i>I</i...

Full description

Bibliographic Details
Main Authors: Susanne Rinné, Annemarie Oertli, Claudia Nagel, Philipp Tomsits, Tina Jenewein, Stefan Kääb, Silke Kauferstein, Axel Loewe, Britt Maria Beckmann, Niels Decher
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:International Journal of Molecular Sciences
Subjects:
potassium channel
KCNQ1
KvLQT1
LQTS
Romano-Ward syndrome
Online Access:https://www.mdpi.com/1422-0067/24/2/1350

Internet

https://www.mdpi.com/1422-0067/24/2/1350

Similar Items