Intranasal administration of collagenase develops cerebral microbleeds and vascular dementia in mice: In vivo pilot study
Objective: To establish a new animal model of lobar cerebral microbleeds (CMBs), we examined whether intranasal administration of collagenase induced CMBs in young mice which did not have hypertensive pathologic features. Methods: We used thirty-two male CD1 mice (8–10 weeks old), which were receive...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
KeAi Communications Co., Ltd.
2023-12-01
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| Series: | Brain Hemorrhages |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2589238X23000219 |