Aging‐Associated ALKBH5‐m6A Modification Exacerbates Doxorubicin‐Induced Cardiomyocyte Apoptosis Via AT‐Rich Interaction Domain 2
Background Chemotherapy‐induced cardiovascular disease is a growing concern in the elderly population who have survived cancer, yet the underlying mechanism remains poorly understood. We investigated the role of ALKBH5 (AlkB homolog 5), a primary N6‐methyladenosine (m6A) demethylase, and its involve...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2024-01-01
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Series: | Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease |
Subjects: | |
Online Access: | https://www.ahajournals.org/doi/10.1161/JAHA.123.031353 |