Altered Caffeine Metabolism Is Associated With Recurrent Hypoglycemia in Type 2 Diabetes Mellitus: A UPLC–MS-Based Untargeted Metabolomics Study

Altered Caffeine Metabolism Is Associated With Recurrent Hypoglycemia in Type 2 Diabetes Mellitus: A UPLC–MS-Based Untargeted Metabolomics Study

BackgroundRecurrent hypoglycemia (RH) is well known to impair awareness of hypoglycemia and increase the risk of severe hypoglycemia; the underlying mechanism requires further understanding. We aimed to investigate the metabolic characteristic profile for RH in type 2 diabetes mellitus (T2DM) patien...

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Bibliographic Details
Main Authors: Wang Lijing, Ke Sujie, Wang Linxi, Huang Lishan, Qi Liqin, Zhan Zhidong, Wu Kejun, Zhang Mengjun, Liu Xiaoying, Liu Xiaohong, Liu Libin
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Endocrinology
Subjects:
Type 2 diabetes mellitus
recurrent hypoglycemia
metabolomics
liquid chromatography-mass spectrometry
caffeine
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.843556/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2022.843556/full

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