Met kinetic signature derived from the response to HGF/SF in a cellular model predicts breast cancer patient survival.

Met kinetic signature derived from the response to HGF/SF in a cellular model predicts breast cancer patient survival.

To determine the signaling pathways leading from Met activation to metastasis and poor prognosis, we measured the kinetic gene alterations in breast cancer cell lines in response to HGF/SF. Using a network inference tool we analyzed the putative protein-protein interaction pathways leading from Met...

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Bibliographic Details
Main Authors: Gideon Y Stein, Nir Yosef, Hadar Reichman, Judith Horev, Adi Laser-Azogui, Angelique Berens, James Resau, Eytan Ruppin, Roded Sharan, Ilan Tsarfaty
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3457970?pdf=render

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http://europepmc.org/articles/PMC3457970?pdf=render

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