Protein phosphatase 2A anchoring disruptor gene therapy for familial dilated cardiomyopathy

Protein phosphatase 2A anchoring disruptor gene therapy for familial dilated cardiomyopathy

Familial dilated cardiomyopathy is a prevalent cause of heart failure that results from the mutation of genes encoding proteins of diverse function. Despite modern therapy, dilated cardiomyopathy typically has a poor outcome and is the leading cause of cardiac transplantation. The phosphatase PP2A a...

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Bibliographic Details
Main Authors: Xueyi Li, Jinliang Li, Anne-Maj Samuelsson, Hrishikesh Thakur, Michael S. Kapiloff
Format: Article
Language:English
Published: Elsevier 2024-06-01
Series:Molecular Therapy: Methods & Clinical Development
Subjects:
dilated cardiomyopathy
PP2A
adeno-associated virus
gene therapy
Online Access:http://www.sciencedirect.com/science/article/pii/S2329050124000494

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http://www.sciencedirect.com/science/article/pii/S2329050124000494

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