Emerging role of hypoxia-inducible factor-1α in inflammatory autoimmune diseases: A comprehensive review

Emerging role of hypoxia-inducible factor-1α in inflammatory autoimmune diseases: A comprehensive review

Hypoxia-inducible factor-1α (HIF-1α) is a primary metabolic sensor, and is expressed in different immune cells, such as macrophage, dendritic cell, neutrophil, T cell, and non-immune cells, for instance, synovial fibroblast, and islet β cell. HIF-1α signaling regulates cellular metabolism, triggerin...

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Bibliographic Details
Main Authors: Yang-Yang Tang, Da-Cheng Wang, You-Qiang Wang, An-Fang Huang, Wang-Dong Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Immunology
Subjects:
immune cell
inflammation
autoimmune diseases
HIF-1α
signaling pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1073971/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.1073971/full

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