Partridge tea polyphenols alleviated STZ-induced diabetic nephropathy by regulating Keap1/Nrf2/ARE signaling pathway in C57BL/6 mice

Partridge tea polyphenols alleviated STZ-induced diabetic nephropathy by regulating Keap1/Nrf2/ARE signaling pathway in C57BL/6 mice

The present work investigated the effect of Partridge tea polyphenols (PTP) on streptozotocin (STZ)‑induced diabetic mice as well as the underlying mechanism with rosiglitazone as positive control. Administration with PTP (250 or 500 mg/kg) for 5 weeks, compared to the diabetic nephropathy control g...

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Bibliographic Details
Main Authors: Mantong Zhao, Keke Meng, Meihui Zhao, Haohao Shi, Zhongyuan Liu, Yonghuan Yun, Weimin Zhang, Zhouwei Duan, Guanghua Xia
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:Journal of Functional Foods
Subjects:
PTP
Diabetic nephropathy
Oxidative stress
Keap1/Nrf2/ARE signal pathway
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464624001294

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http://www.sciencedirect.com/science/article/pii/S1756464624001294

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