An Efficient New Route to Dihydropyranobenzimidazole Inhibitors of HCV Replication
A class of dihydropyranobenzimidazole inhibitors was recently discovered that acts against the hepatitis C virus (HCV) in a new way, binding to the IRES-IIa subdomain of the highly conserved 5' untranslated region of the viral RNA and thus preventing the ribosome from initiating translation. Ho...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2010-12-01
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Series: | Molecules |
Subjects: | |
Online Access: | http://www.mdpi.com/1420-3049/16/1/281/ |