Thermosensitive hydrogel loaded with concentrated growth factors promote bone repair in segmental bone defects

Thermosensitive hydrogel loaded with concentrated growth factors promote bone repair in segmental bone defects

Treating critical-size bone defects beyond the body’s self-healing capacity is a challenging clinical task. In this study, we investigate the effect of concentrate growth factors (CGFs) loaded Poloxamer 407 hydrogel on the viability and osteogenic differentiation potential of bone marrow mesenchymal...

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Bibliographic Details
Main Authors: Yuxin Zhang, Tianchang Wang, Dahe Zhang, Jiayi Li, Xiaokun Yue, Weiqing Kong, Xiaoding Gu, Zixian Jiao, Chi Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
bone marrow mesenchymal stem cells
concentrate growth factor
hydrogel
bone defects
bone generation
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2022.1039117/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2022.1039117/full

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