Transcriptome-wide analysis of trigeminal ganglion and subnucleus caudalis in a mouse model of chronic constriction injury-induced trigeminal neuralgia

Transcriptome-wide analysis of trigeminal ganglion and subnucleus caudalis in a mouse model of chronic constriction injury-induced trigeminal neuralgia

Trigeminal neuropathic pain (TNP) induces mechanical allodynia and hyperalgesia, which are known to alter gene expression in injured dorsal root ganglia primary sensory neurons. Non-coding RNAs (ncRNAs) have been linked to TNP. However, the functional mechanism underlying TNP and the expression prof...

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Bibliographic Details
Main Authors: Xiaona Cui, Bo Qin, Chaoyun Xia, Hong Li, Zhiye Li, Zhisong Li, Abdul Nasir, Qian Bai
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Pharmacology
Subjects:
neuropathic pain
allodynia
hyperalgesia
differentially expressed genes
RNA sequencing
non-coding RNAs
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1230633/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2023.1230633/full

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