Regulatory effect of TLR3 signaling on staphylococcal enterotoxin-induced IL-5, IL-13, IL-17A and IFN-γ production in chronic rhinosinusitis with nasal polyps

Regulatory effect of TLR3 signaling on staphylococcal enterotoxin-induced IL-5, IL-13, IL-17A and IFN-γ production in chronic rhinosinusitis with nasal polyps

Background: Toll-like receptor 3 (TLR3) is expressed in upper airways, however, little is known regarding whether Toll-like receptor 3 (TLR3) signals exert a regulatory effect on the pathogenesis of chronic rhinosinusitis with nasal polyps (CRSwNP), especially on eosinophilic inflammation. We sought...

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Bibliographic Details
Main Authors: Mitsuhiro Okano, Tazuko Fujiwara, Shin Kariya, Takaya Higaki, Sei-ichiro Makihara, Takenori Haruna, Yasuyuki Noyama, Takahisa Koyama, Ryotaro Omichi, Yorihisa Orita, Kentaro Miki, Kengo Kanai, Kazunori Nishizaki
Format: Article
Language:English
Published: Elsevier 2016-01-01
Series:Allergology International
Subjects:
Chronic rhinosinusitis with nasal polyps
IL-5
IL-10
Poly(IC)
Toll-like receptor
Online Access:http://www.sciencedirect.com/science/article/pii/S1323893015001793

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http://www.sciencedirect.com/science/article/pii/S1323893015001793

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