Primary glia cells from bank vole propagate multiple rodent-adapted scrapie prions

Abstract Since the beginning prion research has been largely dependent on animal models for deciphering the disease, drug development or prion detection and quantification. Thereby, ethical as well as cost and labour-saving aspects call for alternatives in vitro. Cell models can replace or at least...

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Bibliographic Details
Main Authors: Karla A. Schwenke, Joo-Hee Wälzlein, Agnieszka Bauer, Achim Thomzig, Michael Beekes
Format: Article
Language:English
Published: Nature Portfolio 2022-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-06198-4