The Effect of Silencing the Genes Responsible for the Level of Sphingosine-1-phosphate on the Apoptosis of Colon Cancer Cells

The Effect of Silencing the Genes Responsible for the Level of Sphingosine-1-phosphate on the Apoptosis of Colon Cancer Cells

Sphingosine-1-phosphate (S1P) and ceramides (Cer) are engaged in key events of signal transduction, but their involvement in the pathogenesis of colorectal cancer is not conclusive. The aim of our study was to investigate how the modulation of sphingolipid metabolism through the silencing of the gen...

Full description

Bibliographic Details
Main Authors: Adam R. Markowski, Arkadiusz Żbikowski, Piotr Zabielski, Urszula Chlabicz, Patrycja Sadowska, Karolina Pogodzińska, Agnieszka U. Błachnio-Zabielska
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:International Journal of Molecular Sciences
Subjects:
gene silencing
sphingosine-1-phosphate
ceramides
cellular apoptosis
colon cancer cells
Online Access:https://www.mdpi.com/1422-0067/24/8/7197

Internet

https://www.mdpi.com/1422-0067/24/8/7197

Similar Items