Aspernolide A Inhibits the Proliferation of Human Laryngeal Carcinoma Cells through the Mitochondrial Apoptotic and STAT3 Signaling Pathways

Aspernolide A Inhibits the Proliferation of Human Laryngeal Carcinoma Cells through the Mitochondrial Apoptotic and STAT3 Signaling Pathways

Aspernolide A, a butyrolactone secondary metabolite, was purified from the endophytic fungus Cladosporium cladosporioides derived from roots of Camptotheca acuminata Decne. In this study, the antitumor activity and mechanisms of aspernolide A on human laryngeal cancer Hep-2 and TU212 cells were stud...

Full description

Bibliographic Details
Main Authors: Chang Liu, Hong Liu, Yanzhang Wen, Huiqi Huang, Ji Hao, Yibing Lv, Rui Qin, Xinzhou Yang
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Molecules
Subjects:
aspernolide A
camptotheca acuminata decne
cladosporium cladosporioides
anticancer
laryngeal cancer
apoptosis
mitochondrial pathway
STAT3
Online Access:http://www.mdpi.com/1420-3049/24/6/1074

Internet

http://www.mdpi.com/1420-3049/24/6/1074

Similar Items