The Evolution of Clinically Aggressive Triple-Negative Breast Cancer Shows a Large Mutational Diversity and Early Metastasis to Lymph Nodes

The Evolution of Clinically Aggressive Triple-Negative Breast Cancer Shows a Large Mutational Diversity and Early Metastasis to Lymph Nodes

In triple-negative breast cancer (TNBC), only 30% of patients treated with neoadjuvant chemotherapy achieve a pathological complete response after treatment and more than 90% die due to metastasis formation. The diverse clinical responses and metastatic developments are attributed to extensive intra...

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Bibliographic Details
Main Authors: Héctor Martínez-Gregorio, Ernesto Rojas-Jiménez, Javier César Mejía-Gómez, Clara Díaz-Velásquez, Rosalía Quezada-Urban, Fernando Vallejo-Lecuona, Aldo de la Cruz-Montoya, Fany Iris Porras-Reyes, Víctor Manuel Pérez-Sánchez, Héctor Aquiles Maldonado-Martínez, Maybelline Robles-Estrada, Enrique Bargalló-Rocha, Paula Cabrera-Galeana, Maritza Ramos-Ramírez, Yolanda Irasema Chirino, Luis Alonso Herrera, Luis Ignacio Terrazas, Cecilia Frecha, Javier Oliver, Sandra Perdomo, Felipe Vaca-Paniagua
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Cancers
Subjects:
triple-negative breast cancer
tumor evolution
metastasis
lymph nodes
early divergence
targeted therapies
Online Access:https://www.mdpi.com/2072-6694/13/20/5091

Internet

https://www.mdpi.com/2072-6694/13/20/5091

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