Identification of Known and Novel Recurrent Viral Sequences in Data from Multiple Patients and Multiple Cancers

Identification of Known and Novel Recurrent Viral Sequences in Data from Multiple Patients and Multiple Cancers

Virus discovery from high throughput sequencing data often follows a bottom-up approach where taxonomic annotation takes place prior to association to disease. Albeit effective in some cases, the approach fails to detect novel pathogens and remote variants not present in reference databases. We have...

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Bibliographic Details
Main Authors: Jens Friis-Nielsen, Kristín Rós Kjartansdóttir, Sarah Mollerup, Maria Asplund, Tobias Mourier, Randi Holm Jensen, Thomas Arn Hansen, Alba Rey-Iglesia, Stine Raith Richter, Ida Broman Nielsen, David E. Alquezar-Planas, Pernille V. S. Olsen, Lasse Vinner, Helena Fridholm, Lars Peter Nielsen, Eske Willerslev, Thomas Sicheritz-Pontén, Ole Lund, Anders Johannes Hansen, Jose M. G. Izarzugaza, Søren Brunak
Format: Article
Language:English
Published: MDPI AG 2016-02-01
Series:Viruses
Subjects:
sequence clustering
taxonomic characterisation
novel sequence identification
next generation sequencing
cancer causing viruses
oncoviruses
assay contamination
Online Access:http://www.mdpi.com/1999-4915/8/2/53

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http://www.mdpi.com/1999-4915/8/2/53

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