Zinc complex of 3,5-di-tert-butyl salicylate inhibits viability, migration, and invasion in triple-negative breast cancer cells

Abstract The zinc complex of 3,5-di-tert-butyl salicylate (Zn{[CH3)3C]2Sal}2 2−) is a zinc ion chelate of salicylate. In this study, we found that this compound inhibits viability, invasion, and migration and induces apoptosis in triple-negative breast cancer 4T1 cells. RNA-seq showed that the expre...

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Bibliographic Details
Main Authors: Heng Chen, Dong Wang, Limei Fan, Zixin Liu, Weiran Zhang, Jinhua Xu, Yunyi Liu
Format: Article
Language:English
Published: Nature Portfolio 2022-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-08704-0