Dynamic regulation of proximal tubular autophagy from injury to repair after ischemic kidney damage

Dynamic regulation of proximal tubular autophagy from injury to repair after ischemic kidney damage

Abstract Background The role of proximal tubular autophagy in repairing kidney injury following ischemia remains unclear. Methods In this study, we utilized mice with conditional deletion of the Atg5 gene in proximal tubules and monitored the long-term dynamic regulation of autophagy following ische...

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Bibliographic Details
Main Authors: Yuhong Gong, Wei Zhu, Yongqiang Li, Tao Lu, Jiexing Tan, Changsheng He, Luodan Yang, Yufeng Zhu, Li Gong
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Cellular & Molecular Biology Letters
Subjects:
Autophagy
Proximal tubule
Acute kidney injury
Interstitial fibrosis
Online Access:https://doi.org/10.1186/s11658-024-00663-w

Internet

https://doi.org/10.1186/s11658-024-00663-w

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