RNA chaperones buffer deleterious mutations in E. coli

Both proteins and RNAs can misfold into non-functional conformations. Protein chaperones promote native folding of nascent polypeptides and refolding of misfolded species, thereby buffering mutations that compromise protein structure and function. Here, we show that RNA chaperones can also act as mu...

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Bibliographic Details
Main Authors: Marina Rudan, Dominique Schneider, Tobias Warnecke, Anita Krisko
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-03-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/04745