iTRAQ proteomic analysis of exosomes derived from synovial fluid reveals disease patterns and potential biomarkers of Osteoarthritis

Abstract Exosomes extracted from synovial fluid (SF-exo) reflect the status of their originating cells. The proteomic profiles of SF-exo are important for the diagnosis of osteoarthritis (OA). To delineate the proteomic differences between SF-exo from OA patients and healthy individuals, a quantitat...

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Bibliographic Details
Main Authors: Xiaomin Wu, Huaiming Li, Fengzhen Meng, Tun Hing Lui, Xiaohua Pan
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Online Access:https://doi.org/10.1186/s13018-024-05336-0