Antibacterial and Antitubercular Activities of Cinnamylideneacetophenones

Antibacterial and Antitubercular Activities of Cinnamylideneacetophenones

Cinnamaldehyde is a natural product with broad spectrum of antibacterial activity. In this work, it was used as a template for design and synthesis of a series of 17 cinnamylideneacetophenones. Phenolic compounds 3 and 4 exhibited MIC (minimum inhibitory concentration) and MBC (minimum bactericidal...

Full description

Bibliographic Details
Main Authors: Carlos R. Polaquini, Guilherme S. Torrezan, Vanessa R. Santos, Ana C. Nazaré, Débora L. Campos, Laíza A. Almeida, Isabel C. Silva, Henrique Ferreira, Fernando R. Pavan, Cristiane Duque, Luis O. Regasini
Format: Article
Language:English
Published: MDPI AG 2017-10-01
Series:Molecules
Subjects:
cinnamaldehyde
cinnamylideneacetophenone
antimicrobial
antibacterial
antitubercular
Mycobacterium
Claisen-Schmidt reaction
Online Access:https://www.mdpi.com/1420-3049/22/10/1685

Internet

https://www.mdpi.com/1420-3049/22/10/1685

Similar Items