The Potential Transcriptomic and Metabolomic Mechanisms of ATO and ATRA in Treatment of FLT3-ITD Acute Myeloid Leukemia

The Potential Transcriptomic and Metabolomic Mechanisms of ATO and ATRA in Treatment of FLT3-ITD Acute Myeloid Leukemia

Background Acute myeloid leukemia (AML) with Fms-like tyrosine kinase 3 gene internal tandem duplication (FLT3-ITD) mutations has a poor prognosis. The combination of arsenic trioxide (ATO) and all-trans retinoic acid (ATRA) has a synergistic killing effect on leukemia cells with FLT3-ITD mutation....

Full description

Bibliographic Details
Main Authors: Chun-Jin Peng MD, Zhong Fan MD, Jie-Si Luo MD, Li-Na Wang MD, Yu Li MD, Cong Liang MD, Xiao-Li Zhang MD, Xue-Qun Luo MD, Li-Bin Huang MD, Yan-Lai Tang MD
Format: Article
Language:English
Published: SAGE Publishing 2024-01-01
Series:Technology in Cancer Research & Treatment
Online Access:https://doi.org/10.1177/15330338231223080

Internet

https://doi.org/10.1177/15330338231223080

Similar Items